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Difference between High on something and Low on something

high on something—(sl.)

1. under the influence of a drug or alcohol:

  • It is far safer to drive a car when high on marihuana than when drunk.

2. keen on smth.; enthusiastic about smth.:

  • “I am not high on the Thieu brand of Government,” he said, noting that 40,000 people had been executed by it.

low on somethingdeficient in smth.; short of smth.:

  • John brewed instant coffee. He was low on sugar.