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Take it on the nose vs Take it through the nose

take it on the nose —(sl.) meet misfortune or defeat courageously (also: take it on the chin):

  • And as the 1980s saw labor take it on the nose when choosing to strike, so the late 1990s have been an era of high-stakes labor wins.

take it through the nose—(U.S. Drug users) inhale cocaine:

  • He went into the john, and most of us knew he had to take it through the nose right then.

Note: The expression does not correlate in meaning with the phrase pay through the nosepay too much for smth.:

  • It’s a terrible car, and what annoys me is that I paid through the nose for it.