Blameworthy, guilty, culpable are comparable when they mean deserving reproach and punishment for a wrong, sinful, or criminal act, practice, or condition.
One (as a person or his act or work) is blameworthy that deserves blame or criticism and must suffer or receive reproach, censure, or even more severe punishment,
A person is guilty who is justly chargeable with responsibility for a delinquency, crime, or sin, either in his own knowledge or in that of others, by his confession or by proof (often legal proof) of his responsibility; the term may stress either the fact that guilt has been proved or the fact or the fear of resulting punishment.
Often the term suggests merely a state of mind (as a consciousness that one has committed a sin or a crime or a fear that one is justly suspected of wrongdoing or of a misdeed).
A person is culpable who has been shown to be blameworthy and open to severe censure or condemnation.
The term is also applicable to a blameworthy act, condition, or practice for which one is responsible or which leads to wrong or harm.