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Difference between Do one’s worst and Make the worst of it

do one’s worst—do one’s utmost in evil or mischief:

  • Out of sheer revenge, he did his worst to blacken her character.

make the worst of itexperience the worst aspect of a situation:

  • Having married, they immediately proceeded, as if by mutual consent, to make the worst of it.

See also: have the best of it / make the best of it.