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Difference between Have a new lease of life and Make a new life for oneself

have a new lease of lifefind new enthusiasm and energy (after a period of illness or sadness):

  • I’m able to do much more which is absolutely great and I have a new lease of life.

make a new life for oneselfmove to another place, change one’s career, etc., especially to recover from an unpleasant experience:

  • After the divorce she moved to Buckingham to make a new life for herself.