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Difference between Make a run and Make a run for it

make a run

1. (coll.) make a rapid journey for a short stay at a place:

  • Would you like to make a run of a day or two to the other side of the Weald?

2. (Air Force) make a target approach in order to attack:

  • One of the fighters made a run at us, but his high speed caused him to misjudge his trajectory.

make a run for it—(also: run for it) run in order to escape from a place or a dangerous situation:

  • It was still raining hard, but we made a run for it.