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Difference between Pick someone’s brains and Prey on someone’s mind

pick someone’s brains—get ideas or information about a subject by asking a person:

  • I would love to pick your brains, so to speak, and see what kind of innovative ideas you could come up with.

Note: The expression does not correlate in meaning with the phrase brain someone—(sl.) hit smb. hard on the head (often used as a threat):

  • The constable threatened to brain him if he didn’t shut up.

prey on someone’s mind —(of anxieties, losses, etc.) afflict or worry a person:

  • When the servants had withdrawn, I found that the unhappy result of the duel was still preying on his mind.