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Take charge of someone vs Take someone in charge

take charge of someoneassume the care of a person; attend to smb.’s needs:

  • Bee was not well for a while, so I took charge of the babe.

take someone in chargearrest a person; take smb. into custody:

  • The constable called at Mr. Johnson’s house and took him in charge.

See also: put someone in charge / put someone on a charge.