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Take it up with someone vs Take up with someone

take it up with someoneask a person to consider the matter in question:

  • Take it up with the insurance company, would you? It’s not worth losing your no-claim bonus.

take up with someoneassociate or become friendly with a person, especially smb. undesirable:

  • The woman he “took up with” was likely enough to be married herself and of roughly the same age as his own wife.

Note: The expression does not correlate in meaning with the phrase take up for someone—support a person in an argument, etc.:

  • “My mom and sisters always took up for me,” Kyle said. “They were always on my side…”